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VNU Institute of Microbiology & Biotechnology

 

I.    Foundation date

Institute of Microbiology and Biotechnology (IMBT) (previously known as Center for Biotechnology), a VNU-associated research institute, was founded on the 24th of May 2007, by the Act 661 QĐ-TTg of the Vietnam Prime Minister.

IMBT is now one of the leading institutions specialized in research and development, training and technology transferring in the field of microbiology and biotechnology in Vietnam.

II. Missions

- Research and development: conduct fundamental and applied studies in the field of microbiology and biotechnology.

- Training: conduct post-graduate training programs and workshops in microbial biotechnology; complete other training tasks assigned by the President of VNU.

- Offer consultant services in microbiology and biotechnology.

- Trial production and technology transfer in microbiology and biotechnology.

III. Staffs

- 45 full-time permanent positions:

+ 01 Assoc. Professor

+ 11 PhDs

+ 14 Ms.Scs,

+ 18 B.Scs

+ 01 Technicians

- 04 contract scientists (retired professors continuing research activities at the institute)

IV. Directorate

Director: Assoc.Prof.Dr. Dương Văn Hợp

E-mail: hopdv@vnu.edu.vn; vanhop93@gmail.com

Tel: +84 437 547 695

Fax: +84 437 547 407

Vice – Director:  Ms. Lê Xuân Tình

Email: lxtinh@gmail.com, tinhlx@vnu.edu.vn

Tel: 043 754 7638               

Fax: 04 37547407        

Vice – Director : PhD. Trịnh Thành Trung

Email: tttrung@vnu.edu.vn

Tel: 043 754 8747              

Fax: 04 37547407        

Vice – Director: PhD. Hoàng Văn Vinh

Email: vinhhv@vnu.edu.vn

Tel: 043 754 7748              

Fax: 04 37547407        

V. Sciences & Training Council: functions as an advisory board for the Director in terms of research & training.

Assoc.Prof.Dr. Dương Văn Hợp  Chairman

Dr. Nguyễn Huỳnh Minh Quyền   Vice-chairman

Dr. Nguyễn Quỳnh Uyển  Secretary

Prof.Dr.(Sci.) Trịnh Tam Kiệt  Member

Prof.Dr.(Sci.) Phạm Thị Trân Châu  Member

Prof.Dr. Nguyễn Lân Dũng  Member

Prof.Dr. Lê Đình Lương Member

Dr. Đinh Thúy Hằng  Member

Dr. Nguyễn Thị Hoài Hà  Member

VI. Laboratories

Vietnam Type Culture Collection

Enzyme and Protein Lab

Fermentation and Bioproduct development Lab

Fungal Strains and Technology Lab

Microbial Biotechnology R&D Lab

Microalgae and Environmental Biology Lab

Microbial Ecology Lab

VII: Research directions

Conduct fundamental researches in the fields of Microbiology, Molecular Biology, Enzyme and Protein and Fermentation Technology:

- Complete and upgrade Vietnam Type Culture Collection so that its size and capability are comparable to those of other culture collections in Southeast Asia. IMBT is on its way to become a key institution (in Vietnam) that can offer services of taxonomic classification and preservation of microorganisms following world-class standards. Furthermore, IMBT will become a key supplier of microbial gene pools for research institutions and manufacturers in Vietnam.

- Study microbial structures and genetics; and engineer strains to improve their performance.

- Study microbial metabolism as the basis for fermentation technology R&D.

- Screen bioactive compounds from microorganisms.

- Study diversity and ecology of microorganisms with the aim for monitoring and treatment of environmental pollution.

Conduct applied studies and realize technological applications:

- Exploit the results of fundamental researches and modern techniques in applied studies in order to contribute to the establishment of a bio-industry in Vietnam.

- Study fermentation processes for the development of new high-quality bioproducts and technologies from microorganisms, in order to gradually replace imported products used in agri-and aqua-culture and environmental protection.

- Approach, apply and develop high technologies related to enzymes and proteins, gene technology and nanotechnology, for the development of high-quality bioproducts used in medicine.

- Integrate research achievements in microbiology, fermentation technology and molecular biology to create new bioproducts for domestic use as well as export, such as biodegradable plastics, biofuel and valuable biologically-produced solvents.

- Initiate and catalyze the transfer of advanced technologies for the development of bioproducts with high socio-economical values.

VIII. Research projects (selective):

National research programs

No

Project

Laboratory

Time

1.

Investigation of technological procedure to produce recombinant proteins, ribosome-inactivating protein possessing potent applicability in medicinal, pharmaceutical and agricultural practice

Enzyme and Protein lab

2001-2004

2.

Investigation of bacterial peptides from medicinal plants

Enzyme and Protein lab

2001-2004

3.

Producing multi-functional insecticidal preparation-Momosertatin (MM) against vegetable larvae.

Enzyme and Protein lab

2001-2004

4.

Research on biological strategies to provide specific biological products for human health from biological resources in Vietnam

Fungal strains and Technology lab

2002 – 2004

5.

Research on the Mycoflora in Vietnam and establish a check-list of Fungi in Vietnam

Fungal strains and Technology lab

2004 – to date

6.

Developing and maintaining the macro fungi gene resources in Vietnam.

Fungal strains and Technology lab

2005 – to date

7.

Genetic evaluation of the some bacterial and actinomycetes resources of Vietnam

Enzyme and Protein lab

2011-2014

8.

Development of bioproducts supporting nitrogen removal in wastewater.

Microbial Ecology lab

2012

 

Ministerial, provincial and VNUH projects

No

Project

Laboratory

Time

1.

Study the main bioactive compounds of perennial Ganoderma, polypore mushrooms with the application in medicine (stimulation immune system, antitumor…)

Fungal strains and Technology lab

2004 – 2005

2.

Investigation the mechanism of antibacterial and anti-inflammation action of Momosertatin preparation isolated from Momordica cochinchinensis seeds and other PPI-rich preparation

Enzyme and Protein lab

2004 – 2005

3.

Study on proteins, proteinase inhibitors (PI) from several medicinal plants in Vietnam

Enzyme and Protein lab

2006 – 2008

4.

Study bacterial groups involving in nitrogen and phosphorus cycles and their application possibilities in the cleaning up of environment.

Microbial Ecology lab

2006 – 2008

5.

Study on enzyme production for animal feed

Enzyme and Protein lab

2006 – 2009

6.

Study on probiotics for animal feed

Fermentation and Bioproduct development lab

2006 – 2010

7.

Study on biological characteristics of some Microcystis strains isolated from Hoan Kiem lake Hanoi and capability of their toxin biodegradation by bacteria.

Microalgae and Environmental biology lab

2007 – 2009

8.

Diversity of Fe(II)-oxydizing, nitrate-reducing bacteria in some ecological habitats and their potential use

Microbial Ecology lab

2007 – 2009

9.

Survey of microorganisms in a dioxin contaminated area and access detoxification possibility of the indigenous species.

Microbial Ecology lab

2007 – 2009

10.

Study the potential use of microalgal strains isolated from Xuanthuy mangrove as food for bivalve mollusc larvae

Microalgae and Environmental biology lab

2009 – 2010

11.

Study on bioactive compounds and potential use as food and anti-cancer drugs of microalgal strains isolated from XuanThuy mangrove in Namdinh province

Microalgae and Environmental biology lab

2009 – 2010

12.

Investigation and study some substances which have antibiotic activities against microorganisms and cancer cell lines from actinomycetes

Enzyme and Protein lab

2009 – 2011

13.

Establising an expression vector of Bacillus subtilis

Enzyme and Protein lab

2010 – 2012

14.

Optimizing cultivation process of some marine algae for the feeding of Geo-Ducklarvae in Vandon, Quang ninh

Microalgae and Environmental biology lab

2011 – 2013

15.

Optimizing conditions for the retrieval and purification of L-lactic used in bioplastic production.

Fermentation and Bioproduct development lab

2011 – 2013

16.

Development of microbial products supporting biogas technology under special environmental conditions

Microbial Ecology lab

2011 – 2013

17.

Establishing a process of the removal of toxic microcystin from blue-green algae Microcytis aeruginosa by heterotrophic bacteria to protect the water environment in Hoankiem lake, Hanoi.

Microalgae and Environmental biology lab

2012 – 2013

 

International collaboration projects

No

Project

Laboratory

Time

1.

“Studies on bioactive compounds from Basidiomycetes in Vietnam”. VIE 08

Fungal strains and Technology lab

1997 – 2003

2.

“Studies on bioactive compounds from Basidiomycetes in Vietnam”. VIE 97

Fungal strains and Technology lab

2002 – 2003

3.

“Studies on bioactive compounds from Basidiomycetes in Vietnam”. VIE 97 phase II

Fungal strains and Technology lab

2004 – 2007

4.

Study retrieval and purification processes for chitinase and chitindeacetylase from microbial fermentation broth.

Fermentation and Bioproduct development lab

2010 – 2012

Education - Training:

Joint Master program between Vietnam and Belgium

IMBT-VNUH organized the Joint Master program in Biotechnology for 2 classes (2008-2010 and 2010-2012). The lectures were given by Professors from University of Liege, Belgium.

Short-term training

With the well-equipped facilities for research on microbiology, biochemistry and molecular biology, IMBT successfully organized training courses on the novel techniques in the fields of microbiology and molecular biology. These training courses were instructed by the international experts, who are involved in the collaborative projects with IMBT.

Workshop on biochemistry and molecular biology techniques

Funded by the International Biochemistry and Molecular Biology Association, Vietnamese Biochemistry Association, together with Department of Biology, University of Education in Hanoi and IMBT-VNUH, organized a workshop entitled "Improvement of Biochemistry and Molecular Biology techniques", 20 – 25/7/2011.

Workshop on classification of useful microorganisms isolated from soil

The workshop "Methods of classification of useful organisms (fungi, bacteria) isolated from soil" was organized on May 24-28, 2010 at IMBT, together with Vietnam Academy of Agricultural Science (VAAS) and Agriculture and Technology project (AST). Trainees are students, researchers, lecturers from university and institute for agriculture.

Workshop on fermentation processes of microorganisms to retrieve biomass

Fermentation and bioproduct development lab, IMBT often organizes workshop on microbial fermentation processes and test product quality for other groups. Trainees learn the theory and perform experiments including preparing strains, fermentation and testing quality, purity and cell density of the products.

International collaboration

Collaboration forms:

International collaboration programs are in the forms of:

- Implementation of R&D projects for exchanging knowledge and methodology.

- Technology transfer.

- Training and staff exchange.

- Short-term training courses andworkshops.

- Long-term training: scientific researchers, Ms., PhDs.

- Holding scientific conferences and meetings in Vietnam.

Collaboration projects:

Collaboration with international culture collections in taxonomic classification and quality control of microbial strains and in studying microbial diversity:

- NBRC (NITE Biological Resource Center), Japan

- Japan Collection of Microorganisms (JCM), Riken, Japan

- Chinese General Microbiological Culture Collection Center (CGMCC), China

Collaboration in developing biotechnology applications in Agriculture, Food Industry and Environment Protection.

University of Liege, Belgium

Collaboration between IMBT, VNUH and University of Liege, Belgium on these following aspects:

- Study on chitosan and chitindeacetylase from microorganisms to modify chitin for plant protection

- Study on lactic acid bacteria to produce lactic acid

University of Osaka, Japan:

Collaboration between IMBT and International Center for Biotechnology, University of Osaka, Japan is under JSPS project. The collaboration focuses on bioactive compounds from microorganisms, especially from bacteria and actinomycetes.

National Institute of Technology and Evaluation (NITE), Japan

Collaboration project “Taxonomic and Ecological Studies of Microorganisms in Vietnam and the Utilization” was established in 2004, including two phases. Phase I (2004-2010) focused on diversity study (especially on fungi and actinomycetes) of Vietnam National forests. Phase II (2011- presence) focuses on the application of microorganisms isolated in Vietnam and stored at VTCC and NITE.

Shibaura Institute of Technology, Japan

Collaboration with International Center for Biotechnology (ICB), Shibaura Institute of Technology (SIT), Japan was established in 2008 with two main projects:

- Isolation of bacteria capable of oxidizing polycyclic aromatic hydocarbon (PAH), including dioxin, and application in environmental detoxification.

- Study on diversity of bacteria capable of oxidizing methane in Vietnam, especially in marine environment, and application in converting methane to methanol or in providing protein source for animal feeds.

Jena University, Germany

Collaboration with Jena University, Germany was established in 2006, focusing on extraction and investigation of bioactive compounds from macro fungi in Vietnam.

Address

Institute of Microbiology and Biotechnology

Building E2- 144 Xuân Thủy, Cầu Giấy, Ha Noi

Telephone: (04) 37547407; Fax: (04) 37547407

Website: http://www.imbt.vnu.edu.vn

 

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